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Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

✍ Scribed by Paula I. Moreira; Cristina Carvalho; Xiongwei Zhu; Mark A. Smith; George Perry


Book ID
116270826
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
723 KB
Volume
1802
Category
Article
ISSN
0925-4439

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## Abstract Abnormalities in mitochondrial function relate to the spectrum of pathological changes seen in Alzheimer's disease. Here we review the causes and consequences of mitochondrial disturbances in Alzheimer's disease as well as how this information might impact on therapeutic approaches to t