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Mitochondrial DNA Rearrangements in Health and Disease-A Comprehensive Study

✍ Scribed by Damas, Joana; Samuels, David C.; Carneiro, João; Amorim, António; Pereira, Filipe

Book ID
121269888
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
1000 KB
Volume
35
Category
Article
ISSN
1059-7794

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## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1‐methyl‐4‐