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Response characteristics of the mitochondrial DNA genome in developmental health and disease

✍ Scribed by Thomas B. Knudsen; Maia L. Green


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
196 KB
Volume
72
Category
Article
ISSN
1542-975X

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The activity of cytochrome oxidase (CO), the terminal enzyme of the mitochondrial electron transport chain, has been reported to be lower in the brains of Alzheimer disease (AD) patients. This suggests that a modification of mitochondrial DNA (mtDNA) may be responsible for this decrease of CO activi