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Mitochondrial DNA polymorphisms and risk of Parkinson's disease in Spanish population

✍ Scribed by Cecilia Huerta; Mónica G. Castro; Eliecer Coto; Marta Blázquez; René Ribacoba; Luis M. Guisasola; Carlos Salvador; Carmen Martínez; Carlos H. Lahoz; Victoria Alvarez

Book ID
119301732
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
110 KB
Volume
236
Category
Article
ISSN
0022-510X

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✍ Dr. A. H. V. Schapira; I. J. Holt; M. Sweeney; A. E. Harding; P. Jenner; C. D. M 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 479 KB 👁 1 views

## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1‐methyl‐4‐