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Mitochondrial DNA mutations, energy metabolism and apoptosis in aging muscle

✍ Scribed by Amie J. Dirks; Tim Hofer; Emanuele Marzetti; Marco Pahor; Christiaan Leeuwenburgh

Book ID: 116255186
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 301 KB
Volume: 5
Category: Article
ISSN: 1872-9649
DOI: 10.1016/j.arr.2006.03.002

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## Communicated by Henrik Dahl Seven mtDNA mutations (five base substitutions and two deletions) were studied in skeletal muscle samples of 18 human subjects aged 1 hr to 90 years. Quantitative PCR procedures were applied to determine the incidence (frequency of occurrence) and abundance (percentag