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Mitochondrial DNA in Postmortem Brain from Patients with Parkinson's Disease

✍ Scribed by P. Lestienne; I. Nelson; P. Riederer; H. Reichmann; K. Jellinger


Book ID
111176030
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
184 KB
Volume
56
Category
Article
ISSN
0022-3042

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## Abstract The reduced form of nicotinamide adenine dinucleotide coenzyme Q reductase (complex I) activity has recently been shown to be deficient in the substantia nigra of patients dying with Parkinson's disease. This biochemical defect is identical to that produced by the neurotoxin 1‐methyl‐4‐