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Mitochondrial dependence of nerve growth factor-induced mechanical hyperalgesia

✍ Scribed by Carissa Chu; Emma Levine; Robert W. Gear; Oliver Bogen; Jon D. Levine


Book ID
113839725
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
327 KB
Volume
152
Category
Article
ISSN
0304-3959

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Intraspinal and behavioral events were studied in adult rats with nociceptive nerves that were undergoing collateral sprouting into adjacent denervated skin. This sprouting, which is driven by endogenous nerve growth factor (NGF), did not cause hyperalgesia. For comparison, we studied an exogenous N