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Hyperalgesia due to nerve damage: role of nerve growth factor

✍ Scribed by M Theodosiou; R.A Rush; X.F Zhou; D Hu; J.S Walker; D.J Tracey

Book ID
117480262
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
397 KB
Volume
81
Category
Article
ISSN
0304-3959

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Intraspinal and behavioral consequences
Intraspinal and behavioral consequences of nerve growth factor-induced nociceptive sprouting and nerve growth factor-induced hyperalgesia compared in adult rats
✍ Pertens, Evi; Urschel-Gysbers, Bethany A.; Holmes, Michael; Pal, Raveen; Foerste πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 454 KB πŸ‘ 2 views

Intraspinal and behavioral events were studied in adult rats with nociceptive nerves that were undergoing collateral sprouting into adjacent denervated skin. This sprouting, which is driven by endogenous nerve growth factor (NGF), did not cause hyperalgesia. For comparison, we studied an exogenous N