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Mitochondrial AZT metabolism

โœ Scribed by David C. Samuels


Book ID
111741814
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
254 KB
Volume
58
Category
Article
ISSN
1521-6543

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The possibility of tissue-speciยฎc eects regarding mitochondrial sensitivity to AZT was evaluated in this study. When mitochondria isolated from liver, kidney, skeletal and cardiac muscle were oxidizing glutamate, a dose-dependent inhibition by AZT of state 3 respiration was observed; using succinate