๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Missense Polymorphisms in theAdenomatous Polyposis ColiGene and Colorectal Cancer Risk

โœ Scribed by Sean P. Cleary; Hyeja Kim; Marina E. Croitoru; Mark Redston; Julia A. Knight; Steven Gallinger; Robert Gryfe

Publisher
Springer
Year
2008
Tongue
English
Weight
186 KB
Volume
51
Category
Article
ISSN
0012-3706

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

The risk of brain tumours in hereditary
The risk of brain tumours in hereditary non-polyposis colorectal cancer (HNPCC)
โœ H. F. A. Vasen; E. A. C. M. Sanders; B. G. Taal; F. M. Nagengast; G. Griffioen; ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 417 KB ๐Ÿ‘ 2 views

Hereditary non-polyposis colorectal cancer (HNPCC) is known to be associated with several extracolonic cancers, e.g., cancers of the endometrium, stomach, urinary tract, small bowel and ovary. An association between HNPCC and brain tumours has also been reported, although previous risk analysis did

Polymorphisms in inflammatory pathway ge
Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk
โœ Bernd Frank; Michael Hoffmeister; Norman Klopp; Thomas Illig; Jenny Chang-Claude ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 158 KB ๐Ÿ‘ 1 views

## Abstract Chronic inflammation is an established risk factor for colorectal cancer (CRC), and polymorphisms in genes regulating inflammatory processes appear to alter the risk for neoplasia and the efficacy of nonsteroidal antiโ€inflammatory drugs in CRC chemoprevention. We examined the associatio

IGF1 is a modifier of disease risk in he
IGF1 is a modifier of disease risk in hereditary non-polyposis colorectal cancer
โœ Stuart G. Reeves; Dominique Rich; Cliff J. Meldrum; Kim Colyvas; Grzegorz Kurzaw ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 109 KB ๐Ÿ‘ 1 views

## Abstract Patients diagnosed with HNPCC harbouring a confirmed germline mutation in DNA mismatch repair (MMR) genes have an 80% lifetime risk of developing an epithelial malignancy. There is, however, considerable variation in the age of disease onset in these patients. Insulinโ€like growth factor

Life-time risk of different cancers in h
Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (hnpcc) syndrome
โœ Markku Aarnio; Jukka-Pekka Mecklin; Lauri A. Aaltonen; Minna Nystrรถm-Lahti; Heik ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 431 KB ๐Ÿ‘ 1 views

Identification of hereditary non-polyporis colorectal cancer (HNPCC) indicates theoretical life-time risks of 50% for the descendants of an affected family member and of 100% for the true gene carriers. However, besides colorectal cancer (CRC), many other cancer types and sites are also involved, wh

Single nucleotide polymorphisms in the h
Single nucleotide polymorphisms in the hypoxia-inducible factor-1 gene and colorectal cancer risk
โœ Gudrun Knechtel; Joanna Szkandera; Michael Stotz; Gรผnter Hofmann; Uwe Langsenleh ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 77 KB ๐Ÿ‘ 1 views

## Abstract With an incidence of about 300โ€‰000 new cases colorectal cancer (CRC) is the second leading cause of cancerโ€related death in Europe and the United States. Environmental and genetic factors influence CRC risk. Hypoxiaโ€inducible factorโ€1 (HIFโ€1), a heterodimeric protein composed of two sub