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Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies

✍ Scribed by Sandri, M.; Coletto, L.; Grumati, P.; Bonaldo, P.


Book ID
121444830
Publisher
The Company of Biologists Ltd
Year
2013
Tongue
English
Weight
424 KB
Volume
126
Category
Article
ISSN
0021-9533

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Muscle biopsies from patients affected by muscular dystrophies and polymyositis were processed with the method of in situ labeling of nuclear DNA fragmentation in order to assess whether apoptosis occurs in these diseases. Apoptotic nuclei were seen in the mononuclear cell infiltrates in inflammator