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Misoprostol and congenital anomalies

✍ Scribed by Rita Brasil; Helena Lutéscia Coelho; Barbara D'Avanzo; Carlo La Vecchia


Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
48 KB
Volume
9
Category
Article
ISSN
1053-8569

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✦ Synopsis


Purpose- To evaluate the risk of having a baby with congenital anomalies in mothers who used misoprostol during pregnancy.Methods- Hospital-based case - control study from Hospital Chateaubriand, Fortaleza, Brasil. Cases were 37 babies weighing less than 1500 g with congenital anomalies of various types, and the comparison group included 387 infants also weighing less than 1500 g, and without congenital anomalies.Results- The multivariate odds ratio of having a baby with congenital anomalies was 2.4 (95% confidence interval 1.0 - 6.2) in mothers who reported having used misoprostol compared with those who did not.Conclusions- Misoprostol use during pregnancy might be related to a broad spectrum of congenital anomalies in infants. Copyright (c) 2000 John Wiley & Sons, Ltd.


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