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Misonidazole and radiotherapy to treat malignant glioma: A phase II trial of the radiation therapy oncology group

โœ Scribed by Steven C. Carabell; Leonard A. Bruno; Alan S. Weinstein; Melvyn P. Richter; Chu H. Chang; Clare B. Weiler; Robert L. Goodman


Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
780 KB
Volume
7
Category
Article
ISSN
0360-3016

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## BACKGROUND. Efforts to improve local control and survival by increasing the dose of once-daily radiation therapy beyond 70 Gray (Gy) for patients with malignant gliomas have as yet been unsuccessful. Hyperfractionated radiation therapy (HF) should allow for delivery of a higher total dose witho