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A randomized trial of accelerated hyperfractionated radiation therapy and bis-chlorethyl nitrosourea for malignant glioma. A preliminary report of radiation therapy oncology group 83–02

✍ Scribed by Walter J. Curran Jr.; Charles B. Scott; James S. Nelson; Alan S. Weinstein; Theodore L. Phillips; Kevin Murray; A. Jennifer Fischbach; Daniel Yakar; James G. Schwade; William D. Powlis; Diane F. Nelson

Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
862 KB
Volume
70
Category
Article
ISSN
0008-543X

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## BACKGROUND. Efforts to improve local control and survival by increasing the dose of once-daily radiation therapy beyond 70 Gray (Gy) for patients with malignant gliomas have as yet been unsuccessful. Hyperfractionated radiation therapy (HF) should allow for delivery of a higher total dose witho