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miR-146a and Krüppel-like factor 4 form a feedback loop to participate in vascular smooth muscle cell proliferation

✍ Scribed by Sun, Shao-guang; Zheng, Bin; Han, Mei; Fang, Xin-mei; Li, Hui-xuan; Miao, Sui-bing; Su, Ming; Han, Yi; Shi, Hui-jing; Wen, Jin-kun

Book ID: 109851565
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 639 KB
Volume: 12
Category: Article
ISSN: 1469-221X
DOI: 10.1038/embor.2010.172

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Role of Krüppel-like factor 4 in phenoty

Role of Krüppel-like factor 4 in phenotypic switching and proliferation of vascular smooth muscle cells

✍ Bin Zheng; Mei Han; Jin-Kun Wen 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract Phenotypic switching and proliferation of vascular smooth muscle cells (VSMCs) are critical components in the development of many vascular proliferation diseases such as atherosclerosis and restenosis after percutaneous coronary interventions. Krüppel‐like factor 4 (KLF4) has been shown