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miR-141-3p inhibits human stromal (mesenchymal) stem cell proliferation and differentiation

✍ Scribed by Qiu, Weimin; Kassem, Moustapha

Book ID
125797679
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
859 KB
Volume
1843
Category
Article
ISSN
0167-4889

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## Abstract Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between 4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited osteogenesis, while chondrogenesis is unaffected. The reasons for these results may be associated with the inheren