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miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells

✍ Scribed by Tomé, M; López-Romero, P; Albo, C; Sepúlveda, J C; Fernández-Gutiérrez, B; Dopazo, A; Bernad, A; González, M A

Book ID
109842384
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
795 KB
Volume
18
Category
Article
ISSN
1350-9047

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## Abstract Human mesenchymal stem cells (MSCs) reside under hypoxic conditions in vivo, between 4% and 7% oxygen. Differentiation of MSCs under hypoxic conditions results in inhibited osteogenesis, while chondrogenesis is unaffected. The reasons for these results may be associated with the inheren