Minor acidic constituents of vetiver oil

✍ Scribed by Naoki Hanayama; Fusao Kido; Reiko Sakuma; Hisashi Uda; Akira Yoshikoshi

• Publisher: Elsevier Science
• Year: 1968
• Tongue: French
• Weight: 219 KB
• Volume: 9
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)70804-5

✦ Synopsis

Vetiver oil contains some sesquiterpenic carboxylic acids, and recently, the structure (XII) has been suggested for zizanoic acid, the major constituent of the acids, by us (F. K., H. U. and A. Y.)(l). We now report here evidence for the structures (I) and (XIII) assigned to two minor acids, named isovalencenic acid and epizizanoic acid, respectively.

After esterification of a mixture of the whole acids with diazomethane, each carboxylic acid was separated as its methyl ester by careful fractional distillation followed by AgNOs-SiOs chromatography. 1) Isovalencenic acid (I), ClsHesOa*, m.p. 135-137', x (MeOH) 225 rnp (c 8000), 3 (KBr)d25oo, 1670, 1622, 844 cm-', s (CClr) 0.86 (s., 3H), 0.93