Minimization of inflammation in the treatment of bladder tumors by intravesical instillation of Adriamycin
β Scribed by Yoshitada Ohi; Kenichiro Okamoto; Takashi Kawabata; Akinori Hanafusa; Chan Ying Fai; Toshiaki Kakinoki; Motoshi Kawahara; Setsuo Asechi; Nichiro Sakamoto; Shinichi Nagata; Shizuo Yagi
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 477 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0344-5704
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The absorption of Adriamycin (ADM) into the systemic circulation and into different organs including the urinary bladder was investigated in the rat after intravesical instillation of ADM with or without a surface active detergent, Tween 80. The postinstillation plasma concentration of ADM increased
The effects of adriamycin (ADR) and mitomycin C (MMC) as inhibitors of the development of bladder tumors in rats were studied. Six-week-old female F344 rats were divided into nine groups, five of which received 0.05% N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN) in their drinking water for the first 4