Mineral acid salts of lidocaine
β Scribed by Henry M. Koehler; John J. Hefferren
- Publisher
- John Wiley and Sons
- Year
- 1964
- Tongue
- English
- Weight
- 200 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
β¦ Synopsis
condition randomly. Group I-E received 250 mg. each of potassium and magnesium aspartate every 12 hours starting within the first hour of the expcriment. The drug was administered suspendcd iii 5 ml. distilled water directly into the stomach with a No. 18 catheter and syringe. (The potassiuin, but not the magnesium aspartate. would dissolve in the quantity of water used; for this reason only potassium aspartate was administered to groups 11-E and 111-E.) Group 11-E received 200 mg. of potassium aspartate intraperitoneally in 1 ml. distilled water every 12 hours. Group 111-E received 50 mg. of potassium aspartate i.p. every 12 hours in 0.5 ml. of distilled water. Each control group received an equal amount of distilled water administered by the same route as its experimental group.
The rats were placed in individual 5.5 X 9.5-in. cubicles, on wheels, two-thirds submerged in water, which rotated at a constant speed of approximately 2 r.p.m. Food trays were placed in each cubicle so that the animals could feed at any time. The animals remained on these wheels continuously except when they were removed twice a day for the drug administration. The total distance covered by an animal during the day was 0.7 mile. The rats, when exhausted, fell from the wheel into the water and were unable to remount the wheel. Animals were removed from the experiment when they fell into the water after being replaced on the wheel three times during a 15-minute period. This procedure is the same as that employed by Webb and Agnew.
π SIMILAR VOLUMES
## Abstract The oxidative ability of __Thiobacillus ferrooxidans__ in the presence of different concentrations of H~2~SO~4~, HCl, HNO~3~, and their mixtures was investigated. Bacteriological oxidation of FeSO~4~ is expressed as a function of time and acid concentration. For each acid and for their