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Mimotope vaccines: Epitope mimics induce anti-cancer antibodies

โœ Scribed by Angelika B. Riemer; Erika Jensen-Jarolim

Book ID
108152336
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
184 KB
Volume
113
Category
Article
ISSN
0165-2478

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A baboon was immunized with NP-4, a murine monoclonal antibody (MAb) to carcinoembryonic antigen (CEA). Antiidiotype antibodies were purified from the baboon serum by affinity chromatography on a NP-+coupled matrix, followed by adsorption of the non-specific antibodies on an irrelevant MAb. Baboon a