Inhibition by aphidicolin of cell cycle
β
Susumu Ikegami; Shonan Amemiya; Mieko Oguro; Hiroshi Nagano; Yoshitake Mano
π
Article
π
1979
π
John Wiley and Sons
π
English
β 428 KB
## Abstract We have recently found that aphidicolin, a tetracyclic diterpeneβtetraol produced by several fungi, blocks DNA synthesis of sea urchin embryos by interfering with the activity of DNA polymerase Ξ±. These cells fail to proliferate in the presence of aphidicolin. In continuation of these