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Mild reduction of carboxylic acids to alcohols using cyanuric chloride and sodium borohydride

โœ Scribed by Massimo Falorni; Andrea Porcheddu; Maurizio Taddei

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
125 KB
Volume
40
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Several carboxylic acids, including N-Boo, N-Cbz and N-Fmoe amino acids were reduced to the corresponding alcohols by activation of the carboxy function with cyanuric chloride and N-methylmorpholine followed by reduction with aqueous sodium borohydride.

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