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Mild and rapid azide- mediated, palladium catalyzed cleavage of allylester based protecting groups

โœ Scribed by Gideon Shapiro; Dieter Buechler


Book ID
104214733
Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
305 KB
Volume
35
Category
Article
ISSN
0040-4039

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Use of an allylic anchor group and of it
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protected The allylic handle -0-CH2-CH-CH-CH2-0-CH2-CO-has been used in the synthesis of peptide fro ments on aminomethyl polystyrene. The palladium-catalyzed hydrostannolytic cleavage il of t e peptide fragments from the resin occurs under very mild conditions.