Midazolam and myoclonus in neonate
β Scribed by J. F. Magny; A. M. d'Allest; H. Nedelcoux; V. Zupan; M. Dehan
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 245 KB
- Volume
- 153
- Category
- Article
- ISSN
- 0340-6997
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π SIMILAR VOLUMES
Midazolam is a water soluble benzodiazepine, with a short elimination half-life in adults and children. An IV bolus of midazolam 0.2 mg.kg-1 was administered to 10 critically ill neonates receiving intensive care who required sedation. The plasma clearance was 6.85 ml.min-1 and the elimination half-
Midazolam is a water soluble benzodiazepine, with a short elimination half-life in adults and children. An IV bolus (0.2 mg.kg-1) immediately followed by continuous infusion of 0.06 mg.kg-1.h-1 was administered to 15 critically ill neonates at a gestational age of 32.8 weeks, who required sedation f
## Abstract Benign neonatal sleep myoclonus is a syndrome characterized by the occurrence of repetitive myoclonic jerks of the extremities exclusively during nonβrapid eye movement sleep in the early life of healthy newborns. No etiological factors are present. The onset is within the first 15 days
## Abstract This review examines some of the advances in understanding myoclonus over the last 25 years. The classification of myoclonus into cortical, brainstem, and spinal forms has been consolidated, each with distinctive clinical characteristics and physiological mechanisms. New genetic causes
A simple, selective high-performance liquid chromatographic method with ultraviolet detection at 220 nm is described for quantitation of midazolam and its primary metabolite 1-hydroxymidazolam in 100 pL plasma samples from premature infants. A mobile phase of acetonitrile: tetrahydr0furan:phosphate