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Microwave-assisted synthesis of pyrimido[4,5-b][1,6]naphthyridin-4(3H)-ones with potential antitumor activity

✍ Scribed by Insuasty, Braulio; Becerra, Diana; Quiroga, Jairo; Abonia, Rodrigo; Nogueras, Manuel; Cobo, Justo

Book ID: 118264941
Publisher: Elsevier Science
Year: 2013
Tongue: French
Weight: 355 KB
Volume: 60
Category: Article
ISSN: 0223-5234
DOI: 10.1016/j.ejmech.2012.11.037

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## Abstract magnified image Novel 11‐amino‐6‐aryl‐6,7‐dihydroindeno[1,2‐__e__] pyrimido[4,5‐__b__][1,4]diazepin‐5(5a__H__)‐ones 4a‐f were prepared regioselectively by the tricomponent reaction of 4,5,6‐triaminopyrimidine 1, 1,3‐indandione 2 and aromatic aldehydes 3a‐f. The bicomponent approach, us