𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Microwave-assisted synthesis of methyl (1S,2R,4S,5S)-7-aza-5-hydroxybicyclo[2.2.1]heptane-2-carboxylate through unexpected stereoselective substitution reaction

✍ Scribed by Satoru Onogi; Shuhei Higashibayashi; Hidehiro Sakurai


Book ID
113930825
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
903 KB
Volume
53
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Stereoselective synthesis of (+)-(1R,2S,
✍ D. Gautam; B. Venkateswara Rao 📂 Article 📅 2010 🏛 Elsevier Science 🌐 French ⚖ 293 KB

A stereoselective approach for the synthesis of (+)-(1R,2S,5S,7R)-2-hydroxy-exo-brevicomin from L-ascorbic acid has been described. The key steps are highly stereoselective nucleophilic addition reaction on aldehyde 8 and also a single pot transformation of 15 to (+)-(1R,2S,5S,7R)-2-hydroxy-exo-brev

An enantiomerically pure potential toxap
✍ Hansen, Lars Kr. ;Kallenborn, Roland ;Kiprianova, Anastasia ;Nikiforov, Vladimir 📂 Article 📅 2004 🏛 International Union of Crystallography 🌐 English ⚖ 317 KB

Single-crystal X-ray study T = 298 K Mean '(C±C) = 0.003 A Ê R factor = 0.025 wR factor = 0.065 Data-to-parameter ratio = 16.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

First stereoselective synthesis of (1S,2
✍ Henrichfreise, Peter ;Scharf, Hans-Dieter 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 510 KB

## Abstract Starting from 2,3‐__O__‐(3‐pentylidene)‐D‐glyceraldehyde (3), we prepared the bicyclic pheromone (1__S__,2__S__,4__R__,5__R__)‐(−)‐β‐multistriatin (1) on a gram scale. Key steps of the synthesis are a __cis__‐selective Wittig olefination followed by diastereo‐selective Michael addition