Microwave-assisted synthesis and pharmacological studies of novel 5-deazaalloxazine derivatives
✍ Scribed by Vetrivel Nadaraj, Senniappan Thamarai Selvi, Sellappan Mohan, Thangaian Daniel Thangadurai
- Book ID
- 118777977
- Publisher
- Springer-Verlag
- Year
- 2011
- Tongue
- English
- Weight
- 335 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1054-2523
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📜 SIMILAR VOLUMES
The synthesis of the indole core structure was investigated using microwave irradiation. The experimental microwave conditions described allow significant rate enhancements and good yields compared to conventional reaction conditions.
## Abstract A series of 3‐alkyl(aryl)‐4‐(__p__‐hydroxy‐phenyl)‐4,5‐dihydro‐1__H__‐1,2,4‐triazol‐5‐ones **2** were obtained from the reaction of alkyl (aryl) ester ethoxycarbonyl hydrazones **1** with __p__‐hydroxy aniline. The reaction of **1** with 1,4‐diamino benzene (1:1) to afford 3‐alkyl(aryl)