Microwave-assisted oxidation of saturated and unsaturated alcohols with t-butyl hydroperoxide and zeolites

✍ Scribed by Laura Palombi; Francesco Bonadies; Arrigo Scettri

• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 413 KB
• Volume: 53
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(97)10047-3

✦ Synopsis

Under microwave irradiation 3A molecular sieves promote the oxidation of secondary (linear and cyclic) and benzylic alcohols to the corresponding carbonyl compounds by t-butyl hydroperoxide. Under the same conditions, ct,13-unsaturated alcohols are converted into Qt,13-epoxyalcohols in regio-and diastereoselective way. Both oxidative processes can be performed under solvent-free conditions; however, epoxidation ofallylic alcohols is found to proceed with more satisfactory efficiency in saturated aliphatic hydrocarbon (n-hexane or cyclohexane).