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Microwave-Assisted Multi-Component Synthesis of Fused 3-Aminoimidazoles.

โœ Scribed by Sarah M. Ireland; Heather Tye; Mark Whittaker


Book ID
101943781
Publisher
John Wiley and Sons
Year
2003
Weight
116 KB
Volume
34
Category
Article
ISSN
0931-7597

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Microwave-assisted multi-component synth
โœ Sarah M. Ireland; Heather Tye; Mark Whittaker ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 163 KB

A variety of fused 3-aminoimidazoles have been synthesised by a microwave assisted Ugi three-component coupling (3cc) reaction catalysed by scandium triflate in methanol as solvent. Yields of 33-93% have been achieved after just 10 min of microwave irradiation using a simple one-stage procedure. The