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Microwave-assisted Brønsted acidic ionic liquid-promoted one-pot synthesis of heterobicyclic dihydropyrimidinones by a three-component coupling of cyclopentanone, aldehydes, and urea

✍ Scribed by Matiur Rahman; Adinath Majee; Alakananda Hajra

Publisher
Journal of Heterocyclic Chemistry
Year
2010
Tongue
English
Weight
72 KB
Volume
47
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

magnified image A simple and efficient method has been developed for the synthesis of heterobicyclic dihydropyrimidinone derivatives through a solvent‐free one‐pot three‐component condensation of aromatic aldehydes, cyclopentanone, and urea or thiourea in the presence of Brønsted acidic ionic liquid under microwave irradiation. The catalyst can be reused at least six times without any noticeable decrease in catalytic activity. J. Heterocyclic Chem., (2010).

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