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Microwave Activated Solid Support Synthesis of New Antibacterial Quinolones

โœ Scribed by Mazaahir Kidwai; Preeti Misra; Bhavesh Dave; Kumar R. Bhushan; Rajendra K. Saxena; Meena Singh


Publisher
Springer Vienna
Year
2000
Tongue
English
Weight
62 KB
Volume
131
Category
Article
ISSN
0026-9247

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Reaction of 7-amino-3-[5ะˆ-methyl-1ะˆ,3ะˆ,4ะˆ-thiadiazol-2ะˆ-ylthiomethyl]cephalo-sporanic acid with heterocyclic amines using basic alumina under microwave irradiation (MWI) afforded new cephalosporin analogs in shorter reaction time with improved yield as compared to conventional heating. All the synth