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Microspheres as a drug delivery system in cancer therapy

✍ Scribed by Cummings, Jeffrey


Book ID
121226714
Publisher
Informa plc
Year
1998
Tongue
English
Weight
235 KB
Volume
8
Category
Article
ISSN
1354-3776

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Gelatin–methotrexate conjugate microsphe
✍ Pica, Karen (author);Tchao, Ruy (author);Ofner, Clyde M. (author) 📂 Article 📅 2006 🏛 John Wiley and Sons Inc. 🌐 English ⚖ 285 KB

Gelatin-methotrexate microspheres for intra-tumor administration have possibilities for minimizing systemic toxicities of methotrexate (MTX) and overcoming its resistance. Gelatin-MTX conjugates prepared by a carbodiimide reaction were crosslinked with glutaraldehyde to form microspheres (MTX:gelati