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Microwave-treated gelatin microspheres as drug delivery system

✍ Scribed by Maria Angela Vandelli; Marcello Romagnoli; Alessandra Monti; Manuela Gozzi; Paolo Guerra; Francesco Rivasi; Flavio Forni

Book ID
113690509
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
840 KB
Volume
96
Category
Article
ISSN
0168-3659

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Gelatin-methotrexate microspheres for intra-tumor administration have possibilities for minimizing systemic toxicities of methotrexate (MTX) and overcoming its resistance. Gelatin-MTX conjugates prepared by a carbodiimide reaction were crosslinked with glutaraldehyde to form microspheres (MTX:gelati