A calorimetric method is described which can be used for the routine determination of primary and secondary IV-hydroxylamino compounds in drug metabolism studies using microsomal preparations. The assay is carried out on the supernatant obtained after protein precipitation of the incubation mixture.
Microsomal Catalyzed N-Hydroxylation of Guanfacine and Reduction of N-Hydroxyguanfacine
β Scribed by Bernd Clement; Mark Demesmaeker
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 379 KB
- Volume
- 330
- Category
- Article
- ISSN
- 0365-6233
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