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Microscopic Protonation Equilibria of Oxidized Glutathione

✍ Scribed by Noszál, Béla; Szakács, Zoltán

Book ID
126881843
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
105 KB
Volume
107
Category
Article
ISSN
0022-3654

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Microscopic Protonation/Deprotonation Eq
Microscopic Protonation/Deprotonation Equilibria of the Anti-Inflammatory Agent Piroxicam
✍ Krisztina Takács-Novák; József Kökösi; Benjámin Podányi; Béla Noszál; Ruey-Shiua 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 German ⚖ 586 KB

The microscopic ionization behavior of piroxicam was investigated using two different approaches, ie., direct UV spectroscopy and an indirect analogue approach (deductive method). The best microscopic pK, values (pK,,, = 4.60, pK,,, = 5.40, pKa2, = 2.72, and pK,,, = 1.92) were obtained by the deduct