Microscopic properties of elementary Ca2+ release sites in non-excitable cells
β Scribed by David Thomas; Peter Lipp; Stephen C. Tovey; Michael J. Berridge; Wenhong Li; Roger Y. Tsien; Martin D. Bootman
- Book ID
- 114321333
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 362 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0960-9822
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The regulatory mechanism of Ca 2ΓΎ influx into the cytosol from the extracellular space in non-excitable cells is not clear. The ''capacitative calcium entry'' (CCE) hypothesis suggested that Ca 2ΓΎ influx is triggered by the IP 3mediated emptying of the intracellular Ca 2ΓΎ stores. However, there is n
In electrically non-excitable cells the predominant mode of calcium signaling is a biphasic rise in cytosolic calcium concentration. It results from Ca> release from intracellular stores, followed by Ca> in#ux across the plasma membrane. It has been hypothesized that prolonged calcium in#ux may resu