## Determination of dissociation constants of flavonoids by capillary electrophoresis Ionization constants of some flavanols (catechin and epicatechin) and flavonols (kaempherol, fisetin, morin, and quercetin) are determined by capillary zone electrophoresis (CZE). This technique allows the determi
Microscale determination of dissociation constants of multivalent pharmaceuticals by capillary electrophoresis
✍ Scribed by Yasushi Ishihama; Yoshiya Oda; Naoki Asakawa
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 677 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0022-3549
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## Abstract CZE was employed to determine acid–base dissociation constants (p__K__~a~) of ionogenic groups of azahelicenes in methanol (MeOH). Azahelicenes are unique 3‐D aromatic systems, which consist of __ortho__‐fused benzene/pyridine units and exhibit helical chirality. The p__K__~a~ values of