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Microsatellite Mutation (Cag24→18) in the Androgen Receptor Gene in Human Prostate Cancer

✍ Scribed by M.P. Schoenberg; J.M. Hakimi; S.P. Wang; G.S. Bova; J.I. Epstein; K.H. Fischbeck; W.B. Isaacs; P.C. Walsh; E.R. Barrack

Book ID
115574046
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
401 KB
Volume
198
Category
Article
ISSN
0006-291X

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Prostate cancer is considered to be one of the most hormone-dependent human malignancies. As a key mediator of hormonal response, the androgen receptor (AR) is believed to have an important role in the progression of prostate cancer. Mutations in the coding region of the AR gene have been found in b