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Microsatellite Instability of Colorectal Cancer and Adenoma in Synchronous Multiple Colorectal Cancer Patients with Associated Extracolonic Malignancies

โœ Scribed by Eiji Ueda; Toshiaki Watanabe; Hironori Ishigami; Naoyuki Umetani; Shin Sasaki; Shinichiro Koketsu; Hirokazu Nagawa


Book ID
113050421
Publisher
Springer
Year
2001
Tongue
English
Weight
63 KB
Volume
31
Category
Article
ISSN
1436-2813

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Microsatellite instability in colorectal
โœ D. Calistri; S. Presciuttini; G. Buonsanti; P. Radice; I. Gazzoli; V. Pensotti; ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 67 KB ๐Ÿ‘ 2 views

Hereditary non-polyposis colorectal cancer (HNPCC) is a dominantly inherited syndrome linked to DNA-mismatch-repair (MMR) gene defects, which also account for microsatellite instability (MSI) in tumour tissues. Diagnosis is based mainly on family history, according to widely accepted criteria (Amste