Microsatellite instability (MSI) has been reported to occur in a wide variety of sporadic tumours, such as colorectal and gastric cancers. MSI positivity has been associated with a particular clinico-pathologic profile, including the presence of abundant lymphoid infiltration, poor differentiation a
Microsatellite instability in synchronous gastric carcinomas
β Scribed by Hye Seung Lee; Byung Lan Lee; Sun Hee Kim; Dong Kyun Woo; Hee Sung Kim; Woo Ho Kim
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- French
- Weight
- 258 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0020-7136
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Microsatellite instability has been found preferentially in tumours associated with the hereditary non-polyposiscolorectal-cancer (HNPCC) syndrome. This phenotype, manifested as new alleles at microsatellite loci, and often the result of a defective mismatch-repair gene, is seen as allelic mobility
## Background: Microsatellite instability (msi) has been described in many human carcinomas, including gastric carcinomas (gcs). there are inconsistent findings regarding the association of msi with various subsets of gc with specific clinicopathologic features. the objective of this study was to d
Colorectal (CRC) and gastric cancers (GC), the most common gastrointestinal malignancies, have been known to develop occasionally in a same patient. Previous studies have focused on the etiology of patients with multiple primary gastric and colorectal cancer (MPGCC); however, the carcinogenic proces