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Microsatellite instability in IBD-associated neoplastic lesions is associated with hypermethylation and diminished expression of the DNA mismatch repair gene, HMLH1

โœ Scribed by Steven Fleisher, A.; Esteller, Manel; Rashid, Asma; Yin, Jing; Zou, Tong-Tong; Kong, Dehe; Abraham, John M.; Colin Stein, O.; James, Stephen P.; Herman, James G.; Harpaz, Noam; Meltzer, Stephen J.


Book ID
122350286
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
333 KB
Volume
118
Category
Article
ISSN
0016-5085

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Microsatellite instability and protein e
โœ Yuji Takahashi; Kazuya Kondo; Toshiyuki Hirose; Hidewaki Nakagawa; Masaru Tsuyug ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 351 KB

Our previous studies of lung cancer in chromate-exposed workers (chromate lung cancer) have revealed that the frequency of replication error (RER) in chromate lung cancer is very high. We examined whether the RER phenotype of chromate lung cancer is due to an abnormality of DNA mismatch repair prote