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Microsatellite Instability and Therapeutic Consequences in Colorectal Cancer

โœ Scribed by Laghi, Luigi; Malesci, Alberto


Book ID
120035327
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
143 KB
Volume
30
Category
Article
ISSN
0257-2753

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## Abstract Microsatellite instability characterizes a subโ€set of sporadic colorectal cancers (CRCs) as well as CRCs from patients with hereditary nonโ€polyposis colorectal cancer (HNPCC). In order to clarify when the cells acquire a replicationโ€error phenotype (RER) during colorectalโ€tumor progress