## Abstract Microsatellite instability (MSI) has been associated with colitic cancer. However, reported frequency of MSI was varied and the association of MSI with mismatch repair (MMR) deficiency was unclear. In addition, the occurrence of genetic alterations in stromal cells within ulcerative col
Microsatellite instability and loss of heterozygosity in the nondysplastic colonic epithelium of ulcerative colitis
β Scribed by Seiichi Takahashi; Yasuhiro Kojima; Yoshitaka Kinouchi; Kenichi Negoro; Sho Takagi; Hiroyuki Aihara; Nobuya Obana; Keisuke Matsumoto; Nobuo Hiwatashi; Tooru Shimosegawa
- Publisher
- Springer Japan
- Year
- 2003
- Tongue
- English
- Weight
- 199 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0944-1174
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To assess the frequency of loss of heterozygosity (LOH) and microsatellite instability (MI) in oligodendrogliomas, we performed an extensive screening of 16 oligodendrogliomas and nine anaplastic oligodendrogliomas by using 132 microsatellite markers on chromosomes 1 through 12 and 15 through 21. In
## Abstract ## Background. Microsatellite instability (MSI) in head and neck squamous cell carcinoma (HNSCC) has been reported with a wide range of frequencies. The aim of our study was to disclose the frequency and basis of MSI in HNSCC and to correlate MSI and findings on loss of heterozygosity