## Abstract Microsatellite instability characterizes a sub‐set of sporadic colorectal cancers (CRCs) as well as CRCs from patients with hereditary non‐polyposis colorectal cancer (HNPCC). In order to clarify when the cells acquire a replication‐error phenotype (RER) during colorectal‐tumor progress
✦ LIBER ✦
Microsatellite instability: a predictive marker in metastatic colorectal cancer?
✍ Scribed by Gaëtan Des Guetz; Bernard Uzzan; Patrick Nicolas; Olivier Schischmanoff; Jean-François Morere
- Book ID
- 107384344
- Publisher
- Springer-Verlag
- Year
- 2009
- Tongue
- English
- Weight
- 132 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1776-2596
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## BACKGROUND. Microsatellite instability (MI) has been reported in some sporadic colon tumors and in cases of hereditary nonpolyposis colorectal cancer (HNPCC). The criteria for HNPCC have not been fully defined, and clinical criteria are used to identify as many HNPCC patients as possible. To cl