Microsatellite and chromosomal stable colorectal cancers demonstrate poor immunogenicity and early disease recurrence
β Scribed by A. Banerjea; R. E. Hands; M. P. Powar; S. A. Bustin; S. Dorudi
- Book ID
- 109043184
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 245 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1462-8910
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Aberrant DNA methylation, microsatellite instability (MSI) and chromosomal instability (CIN) are wellβcharacterised molecular features of sporadic colorectal cancers (CRCs). In addition to CpG island methylator phenotype (CIMP) associated with MSI, an intermediate methylation subgroup i
## Abstract Most colorectal cancers show either microsatellite or chromosomal instability. A subset of colorectal cancers, especially those diagnosed at young age, is known to show neither of these forms of genetic instability and thus might have a distinct pathogenesis. Colorectal cancers diagnose