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Clinicopathologic and molecular features of sporadic microsatellite- and chromosomal-stable colorectal cancers

✍ Scribed by Guoxiang Cai; Ye Xu; Hongfen Lu; Yingqiang Shi; Peng Lian; Junjie Peng; Xiang Du; Xiaoyan Zhou; Zuqing Guan; Daren Shi; Sanjun Cai


Book ID
106059486
Publisher
Springer
Year
2008
Tongue
English
Weight
229 KB
Volume
23
Category
Article
ISSN
0179-1958

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## Abstract Aberrant DNA methylation, microsatellite instability (MSI) and chromosomal instability (CIN) are well‐characterised molecular features of sporadic colorectal cancers (CRCs). In addition to CpG island methylator phenotype (CIMP) associated with MSI, an intermediate methylation subgroup i