𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Microrobotics and MEMS-Based Fabrication Techniques for Scaffold-Based Tissue Engineering

✍ Scribed by Han Zhang; Dietmar W. Hutmacher; Franck Chollet; Aun Neow Poo; Etienne Burdet

Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
541 KB
Volume
5
Category
Article
ISSN
1616-5187

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Summary: Scaffold based tissue engineering strategies use cells, biomolecules and a scaffold to promote the repair and regeneration of tissues. Although scaffold‐based tissue engineering approaches are being actively developed, most are still experimental, and it is not yet clear what defines an ideal scaffold/cell construct. Solid free form fabrication (SFF) techniques can precisely control matrix architecture (size, shape, interconnectivity, branching, geometry and orientation). The SFF methods enable the fabrication of scaffolds with various designs and material compositions, thus providing a control of mechanical properties, biological effects and degradation kinetics. This paper reviews the application of micro‐robotics and MEMS‐based fabrication techniques for scaffold design and fabrication. It also presents a novel robotic technique to fabricate scaffold/cell constructs for tissue engineering by the assembly of microscopic building blocks.

Scaffold design for a single step pop‐up assembly.

magnified imageScaffold design for a single step pop‐up assembly.

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