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MicroRNAome profiling in benign and malignant neurofibromatosis type 1-associated nerve sheath tumors: evidences of PTEN pathway alterations in early NF1 tumorigenesis

✍ Scribed by Julien Masliah-Planchon, Eric Pasmant, Armelle Luscan, Ingrid Laurendeau…


Book ID
120676761
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
416 KB
Volume
14
Category
Article
ISSN
1471-2164

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Neurofibromatosis type-1 (NF1) is associated with the growth of benign and malignant tumors. Approximately 15% of NF1 patients develop malignant peripheral nerve sheath tumors (MPNSTs), underlining the need to identify specific diagnostic/prognostic biomarkers associated with MPNST development. The