Micro/nanomachining of Polymer Surface for Promoting Osteoblast Cell Adhesion
โ Scribed by Wei He; Kenneth E. Gonsalves; Nikola Batina; Dave B. Poker; Emily Alexander; Michael Hudson
- Book ID
- 111542991
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 472 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1387-2176
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract We have identified the integrin subunits responsible for the initial adhesion of human osteoblastโlike cells to peptideโmodified surfaces. Biomimetic peptide surfaces containing homogenous RGD (ArgโGlyโAsp), homogenous FHRRIKA (PheโHisโArgโArgโIleโLysโAla), and a mixed ratio of FHRRIKA:
## Abstract Heparin/heparan sulfate (HS) plays a key role in cellular adhesion. In this study, we utilized a 12โmer random __Escherichia coli__ cell surface display library to identify the sequence, which binds to heparin. Isolated insert analysis revealed a novel heparinโbinding peptide sequence,
The adhesion and proliferation of endothelial cells can be drastically improved when cultivated on a carbon-deposited polymer surface. When the surface of segmented polyurethane, in which endothelial cells are not capable of proliferating, is modified by carbon deposition, cell adhesion and prolifer